This depends on how you spined the server, basically as long as you configure the clients (i.e. python clients) correctly, there is no issue.
But the auto generated configuration might be off (in the UI when you credentials it tells the clearml-init where the server is and the ports)
I would actually recommend subdomains if this is possible
https://clear.ml/docs/latest/docs/deploying_clearml/clearml_server_config#sub-domain-configuration
wdyt?